Abstract #3711

Comparison of Capability for Molecular-Based Assessment between 3D Gradient Echo-Based and 2D Spin Echo-Based CEST Imaging for Brain Tumors

Kazuhiro Murayama¹, Yoshiharu Ohno², Masao Yui³, Kaori Yamamoto³, Masato Ikedo³, Satomu Hanamatsu², Akiyoshi Iwase⁴, Takashi Fukuba⁴, and Hiroshi Toyama²

¹1) Joint Research Laboratory of Advanced Medical Imaging, Fujita Health University School of Medicine, Toyoake, Japan, ²Radiology, Fujita Health University School of Medicine, Toyoake, Japan, ³Canon Medical Systems Corporation, Otawara, Japan, ⁴Radiology, Fujita Health University Hospital, Toyoake, Japan

No major reports have been evaluated the capability for the molecular-based assessment by 3D chemical exchange saturation transfer (CEST) imaging and compared with 2D CEST imaging. We hypothesized that 3D CEST imaging had equal or better potential for the molecular-based assessment in various brain tumor patients, when compared with 2D CEST imaging. The purpose of this study was to directly compare the capability for molecular-based assessment between 2D and 3D CEST imaging in patients with various brain tumors.

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