Nasopharyngeal carcinoma (NPC) prevails in Southeast Asia. Induction chemotherapy (IC) is recommended as the effective treatment for patients with NPC. However, not all patients respond well to IC. Pretreatment identification of the non-responders may help to make treatment more personalized. The amide proton transfer (APT) MRI can give contrast due to exchangeable backbone amide protons of endogenous mobile proteins and peptides, and APT value in tumor has been reported higher. Therefore, the aim of this study is to evaluate whether APT value before treatment correlate to IC response in NPC.
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