23Na MRI data were acquired on healthy volunteers ~15 mins after either anodal, cathodal, or sham application of tDCS in the motor cortex. Tissue specific [Na] concentration images were obtained using a partial volume correction algorithm previously developed for ASL MRI. There was an average 14% increase in gray matter sodium concentration, [Na]GM, across the group following the anodal tDCS; no significant change was observed for the sham application. Of note, all subjects exhibited a widespread pattern of increased [Na]GM similar to that reported in ASL MRI studies that have measured changes in CBF also following anodal tDCS of M1.
This abstract and the presentation materials are available to members only; a login is required.