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Abstract #3837

Characterization of the triglyceride fatty acid composition and adipocyte size in human adipose tissue using SHORTIE STEAM: in vitro validation

Stefan Ruschke1, Julius Honecker2, Dominik Weidlich1, Claudine Seeliger2, Olga Prokopchuk3, Josef Ecker4, Marcus R. Makowski1, Hans Hauner2, and Dimitrios C. Karampinos1
1Department of Diagnostic and Interventional Radiology, School of Medicine, Technical University of Munich, Munich, Germany, 2Else Kröner Fresenius Center for Nutritional Medicine, Technical University of Munich, Freising, Germany, 3Department of Surgery, Klinikum rechts der Isar, School of Medicine, Technical University of Munich, Munich, Munich, Germany, 4ZIEL Institute for Food & Health; Research Group Lipid Metabolism, Technical University of Munich, Freising, Germany

Short-TR multi-TI multi-TE (SHORTIE) STEAM is a promising technique for the characterization of adipose tissue since it allows the non-invasive simultaneous probing of triglyceride fatty acid composition and triglyceride T1- and T2-relaxation times. The present in vitro study of human adipose tissue aims at the validation of the SHORTIE-assessed triglyceride fatty acid composition with gas chromatography–mass spectrometry and investigates potential correlations of the triglyceride relaxation properties with adipocyte cell size from histology.

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