Abstract #3865

Quantitative evaluation of infrapatellar fat pad in knee osteoarthritis by using hydrogen proton MR spectroscopy (1H-MRS)

Lijie Zhong¹, Mainwen Li¹, Yukun Ding¹, Xintao Zhang¹, Yanjun Chen¹, Yingjie Mei², and Xiaodong Zhang¹

¹Department of Medical Imaging, The Third Affiliated Hospital of Southern Medical University, Guangzhou, China, ²China International Center, Philips Healthcare, Guangzhou, China

Infrapatellar fat pad (IPFP) is an adipose structure of knee joint, which plays an important role in the progression of knee osteoarthritis(KOA). In this paper, we evaluate the fat content and composition of the IPFP in normal subjects and different stages of knee osteoarthritis patients using hydrogen proton MR spectroscopy (¹H-MRS). In addition, we investigate the relationship between the fat content and composition of the IPFP and Hoffa-synovitis. The results showed that the quantitative parameters of the IPFP by MRS were correlated with the progression of KOA and Hoffa-synovitis.

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