Abstract #3892

Inhibition of Urine Amide Proton Transfer Signal with Optimal Scan Parameters in Bladder Cancer

Bo Dai¹, Meiyun Wang ¹, Fengshan Yan¹, Zhiwei Shen², Yan Bai¹, and Nan Meng¹

¹Henan Provincial People's Hospital, Zhengzhou, China, ²Philips healthcare, Beijing, China

In the preliminary experiment, we found that there were hyperintense amide proton transfer weighted (APTw) signal in urine, which may interfere with the contrast of APTw signal in bladder lesion. In this study, we aim to explore the feasibility and features of urine APTw imaging in vitro and in vivo, and inhibite the urine APTw signal for better display of bladder lesions using optimal parameters.

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