Abstract #4001

Whole brain CSF segmentation for consistent zero-referencing and longitudinal study applicability of MEDI+0

Alexey Dimov¹, Thanh Nguyen¹, Susan Gauthier², and Yi Wang³

¹Radiology, Weill Cornell Medicine, New York, NY, United States, ²Neurology, Weill Cornell Medicine, New York, NY, United States, ³Weill Cornell Medicine, New York, NY, United States

The role of CSF segmentation for zero-referenced MEDI+0 is demonstrated. In the present study we show that it is essential to enforce consistency in the CSF mask between different timepoints to ensure value reproducibility and to minimize effects of random shifts in the solution of MEDI+0 minimization

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