To explore the value of Synthetic magnetic resonance imaging (Sy MRI) in the quantitative monitoring of knee joint structural changes and cartilage of amateur marathon runners before and after the whole marathon. Twenty-six knee joints of healthy volunteers who took part in the marathon were scanned by Sy MRI technology one week before the race and within 48 hours after the race. The values of T1, T2 and PD of knee cartilage in whole and different regions before competition were higher than those of 48 hours after the marathon, and the difference was statistically significant
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