Retrospective quantitative evaluation of 103 focal osteolytic lesions of the axial skeleton in virtual-non-calcium bone marrow images of 32 multiple myeloma patients in correlation to hematologic disease status, T1w signal intensity and ADC. Virtual-non-calcium bone marrow imaging allows differentiation between overall active and inactive disease with higher attenuation signifying an increasing likelihood of active disease. This is supported by a significant positive correlation between the attenuation and the ADC, as well as a corresponding inverse correlation to T1w signal intensity.
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