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Abstract #4257

MRI-based tumor localisation after tantalum clip placement for proton beam therapy planning of uveal melanoma 

Myriam Jaarsma-Coes1,2, Teresa Ferreira1, Marina Marinkovic2, Khanh Vu2, Gre Luyten2, Coen Rasch3, Berit Verbist1, and Jan-Willem Beenakker1,2
1Radiology, Leiden University Medical Center, Leiden, Netherlands, 2Ophthalmology, Leiden University Medical Center, Leiden, Netherlands, 3Radiotherapy, Leiden University Medical Center, Leiden, Netherlands

For proton beam therapy (PBRT) of Uveal Melanoma, tantalum clips are surgically sutured on the outside of the eye to mark the tumour edge. To aid in the 3D clip localisation and modelling of the tumor, a dedicated MRI protocol was developed and evaluated. In 51% of the clips, the MRI and per-operative measurements differed less than 1.0mm. In 28% of the clips the discrepancy between the MRI and peroperative measurement was attributed to the complex tumor geometry or anterior tumor localisation. For the majority of the patients MRI added valuable information to the peroperative measurements, improving PBRT planning.

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