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Abstract #4317

Anatomical assessment of retinogeniculate visual pathway tractography: a comparison of multiple tractography methods

Jianzhong He1,2, Fan Zhang2, Guoqiang Xie2,3, Shun Yao2,4, Yuanjing Feng1, Dhiego C.A. Bastos2, Yogesh Rathi2, Nikos Makris2, Ron Kikinis2, Alexandra J. Golby2, and Lauren J. O'Donnell2
1Zhejiang University of Technology, HangZhou, China, 2Harvard Medical School, Boston, MA, United States, 3Nuclear Industry 215 Hospital of Shaanxi Province, XianYang, China, 4The First Affiliated Hospital, GuangZhou, China

In this work, we investigate the performance of four widely used tractography methods (SD-Stream, iFOD1, UKF-1T, and UKF-2T) for the complete retinogeniculate visual pathway (RGVP) reconstruction. Anatomical measurement and expert judgement results indicate that UKF-2T and iFOD1 produce the best performance. The percentage of decussating fibers in the iFOD1 method was more similar to the known percentage from anatomical studies, while the UKF-2T method produced reconstructed RGVPs that were judged to better correspond to the anatomical course of the RGVP.

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