Abstract #4317

Anatomical assessment of retinogeniculate visual pathway tractography: a comparison of multiple tractography methods

Jianzhong He^1,2, Fan Zhang², Guoqiang Xie^2,3, Shun Yao^2,4, Yuanjing Feng¹, Dhiego C.A. Bastos², Yogesh Rathi², Nikos Makris², Ron Kikinis², Alexandra J. Golby², and Lauren J. O'Donnell²

¹Zhejiang University of Technology, HangZhou, China, ²Harvard Medical School, Boston, MA, United States, ³Nuclear Industry 215 Hospital of Shaanxi Province, XianYang, China, ⁴The First Affiliated Hospital, GuangZhou, China

In this work, we investigate the performance of four widely used tractography methods (SD-Stream, iFOD1, UKF-1T, and UKF-2T) for the complete retinogeniculate visual pathway (RGVP) reconstruction. Anatomical measurement and expert judgement results indicate that UKF-2T and iFOD1 produce the best performance. The percentage of decussating fibers in the iFOD1 method was more similar to the known percentage from anatomical studies, while the UKF-2T method produced reconstructed RGVPs that were judged to better correspond to the anatomical course of the RGVP.

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