Abstract #4321

The frontal aslant tract and its role in executive functions: a lesion-symptom study and awake electrical mapping study

Maud Landers¹, Stephan Meesters², Wouter de Baene³, and Geert-Jan Rutten¹

¹Department of Neurosurgery, Elisabeth TweeSteden Hospital, Tilburg, Netherlands, ²Department of mathematics and Computer Science, University of Technology, Eindhoven, Netherlands, ³Department of Cognitive Neuropsychology, University of Tilburg, Tilburg, Netherlands

Currently there is insufficient knowledge about the right frontal aslant tract’s exact cognitive importance. The aim of this study was to investigate the role of the right frontal aslant tract in executive functions via a lesion-symptom approach. The results suggest that the right frontal aslant tract is involved in shifting attention and phonemic fluency. As a follow-up the main findings were tested and validated in an awake mapping study where stimulation of the right frontal aslant tract lead to deficits in executive functioning.

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