Abstract #4330

Distinct Effects on Cognition Caused by the Side of Asymptomatic Carotid Artery Stenosis

Jyun-Ru Chen¹, Chun-Jen Lin^2,3, I-Hui Lee^2,3,4, and Chia-Feng Lu¹

¹National Yang-Ming University, Taipei, Taiwan, ²School of Medicine, National Yang-Ming University, Taipei, Taiwan, ³Neurological Institute, Taipei Veterans General Hospital, Taipei, Taiwan, ⁴Institute of Brain Science, National Yang-Ming University, Taipei, Taiwan

Previous studies reported that the patients with asymptomatic internal carotid stenosis (aICS) had a higher risk of stroke and neurocognitive impairment. However, whether the side of aICS could cause different neurocognitive outcomes was less explored. In this study, significant difference of functional connectivity (FC) was found between the left and right aICS groups. The association between FC and neuropsychological measures (dizziness, immediate and delayed recall verbal memory) revealed by the correlation analysis also presented different profiles between two aICS groups.

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