Successful deployment of 3D liver MRE in the clinical assessment of fibrosis and inflammation requires a single breath-hold sequence to avoid geometric misalignment between different breath-holds and a phase-stable and efficient vibration for adequate wave penetration. We show initial data of Intenso MRE estimating the shear wave speed (Cs [m/s]) and the loss modulus (G’’ [kPa]). Both Cs and G’’ reflect a dependency on Ishak fibrosis and inflammation scores, respectively, in patients with chronic liver disease. In addition, we compare the magnitude of the shear modulus (|G*|) measured with Intenso and to the commonly utilized SE-EPI in such patients.
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