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Abstract #0072

Free Breathing 3D ASL Imaging of the Human Liver using Prospective Motion Correction: Preliminary Results

Jörn Huber1, Daniel Hoinkiss1, Meghashree Channaveerappa1, and Matthias Günther1,2
1Fraunhofer MEVIS, Bremen, Germany, 2Faculty 1 (Physics/Electrical Engineering), University of Bremen, Bremen, Germany

Synopsis

Assessment of liver perfusion can yield valuable information about diseases like carcinoma and cirrhosis. Arterial spin labeling enables contrast-free measurements of liver perfusion with the drawback of increased motion sensitivity. Since timed breathing protocols prolong scan times, a novel prospective motion correction technique is presented, adjusting the initial saturation and image readout to the current position of the liver during the breathing cycle. The presented technique is compatible with highly suppressed signals, typically encountered in modern ASL imaging and achieved a significant decrease of cranial-caudal liver translation in acquired 3D GRASE volumes.

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Keywords