Multi-delay pseudo-continuous arterial spin labeling for perfusion quantification in the spleen
Sergio M. Solis-Barquero1,2, Verónica Aramendia-Vidaurreta1,2, Marta Vidorreta3, Rebeca Echeverria-Chasco1,2, Leyre García-Ruiz1,2, Ana Ezponda1,2, Gorka Bastarrika1,2, and María A. Fernández-Seara1,2
1Departament of Radiology, Clínica Universidad de Navarra, Pamplona, Navarra, Spain, 2IdiSNA, Instituto de Investigación Sanitaria de Navarra, Navarra, Spain, 3Siemens Healthineers, Madrid, Spain
The spleen plays an important role in diseases related to portal circulation. Pseudo-continuous arterial spin labeling (PCASL) was used to assess the Splenic Blood Flow (SBF) using six different post labeling delays in five different healthy volunteers. SBF and ATT maps were generated by fitting the one compartment Buxton kinetic model. This study shows the feasibility of using single and multi-delay PCASL to measure blood flow in the spleen. Obtained SBF values are in agreement with previous studies. PCASL enables a reliable measure of splenic blood flow in healthy volunteers.
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