Abstract #0073

Multi-delay pseudo-continuous arterial spin labeling for perfusion quantification in the spleen

Sergio M. Solis-Barquero^1,2, Verónica Aramendia-Vidaurreta^1,2, Marta Vidorreta³, Rebeca Echeverria-Chasco^1,2, Leyre García-Ruiz^1,2, Ana Ezponda^1,2, Gorka Bastarrika^1,2, and María A. Fernández-Seara^1,2

¹Departament of Radiology, Clínica Universidad de Navarra, Pamplona, Navarra, Spain, ²IdiSNA, Instituto de Investigación Sanitaria de Navarra, Navarra, Spain, ³Siemens Healthineers, Madrid, Spain

Synopsis

The spleen plays an important role in diseases related to portal circulation. Pseudo-continuous arterial spin labeling (PCASL) was used to assess the Splenic Blood Flow (SBF) using six different post labeling delays in five different healthy volunteers. SBF and ATT maps were generated by fitting the one compartment Buxton kinetic model. This study shows the feasibility of using single and multi-delay PCASL to measure blood flow in the spleen. Obtained SBF values are in agreement with previous studies. PCASL enables a reliable measure of splenic blood flow in healthy volunteers.

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