Peripheral arterial disease is a prevalent atherosclerotic disease characterized by atherosclerotic lesions in the limbs. Patients with PAD have been shown to have a delayed phosphocreatine recovery due to chronic ischemia. Patients with PAD may be candidates for revascularization, but outcomes are variable. CrCEST allows for creatine concentrations to be monitored at high spatial resolution, while ASL quantifies perfusion into tissue. We use this combination to revascularization in patients undergoing both endovascular and surgical procedures. Preliminary results link improvement in CrCEST decay curves and improved functional walk scores, while increased perfusion seen on ASL does not necessarily correlate with improvement.
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