T1 relaxation is emerging as a quantitative biomarker for the diagnosis and staging of chronic liver disease. Conventional T1 mapping methods such as variable flip angle and Modified Look-Locker Inversion Recovery, fail to address confounding factors such as B1 inhomogeneities, the presence of fat, and motion. In this work, we propose a novel free-breathing T1 mapping method that addresses multiple confounding factors, combining chemical shift encoded MRI, inversion recovery and stack-of-stars sampling strategy for abdominal T1 mapping.
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