Abstract #0115
Free-Breathing, Fat- and B1-corrected T1 Mapping of the Liver with Chemical Shift Encoded Inversion Recovery MRI
Yavuz Muslu1,2, Ty A. Cashen3, Sagar Mandava4, and Scott B. Reeder1,2,5,6,7
1Department of Biomedical Engineering, University of Wisconsin-Madison, Madison, WI, United States, 2Department of Radiology, University of Wisconsin-Madison, Madison, WI, United States, 3GE Healthcare, Waukesha, WI, United States, 4GE Healthcare, Atlanta, GA, United States, 5Department of Medical Physics, University of Wisconsin-Madison, Madison, WI, United States, 6Department of Medicine, University of Wisconsin-Madison, Madison, WI, United States, 7Department of Emergency Medicine, University of Wisconsin-Madison, Madison, WI, United States
Synopsis
T1 relaxation is emerging as a quantitative biomarker for the diagnosis and staging of chronic liver disease. Conventional T1 mapping methods such as variable flip angle and Modified Look-Locker Inversion Recovery, fail to address confounding factors such as B1 inhomogeneities, the presence of fat, and motion. In this work, we propose a novel free-breathing T1 mapping method that addresses multiple confounding factors, combining chemical shift encoded MRI, inversion recovery and stack-of-stars sampling strategy for abdominal T1 mapping.
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