Abstract #0117

Acute Effects of High-Intensity Exercise on Brain Mechanical Properties and Cognitive Function

Grace McIlvain¹, Emily M Magoon², Rebecca Clements², Alexis Merritt², Lucy V Hiscox³, Hillary Schwarb⁴, and Curtis L Johnson²

¹Biomedical Engineering, University of Delaware, Newark, DE, United States, ²University of Delaware, Newark, DE, United States, ³University of Bath, Bath, United Kingdom, ⁴University of Illinois at Urbana-Champaign, Champaign, IL, United States

Synopsis

Here we use magnetic resonance elastography (MRE) to quantify brain mechanical properties of 30 individuals aged 19-30 immediately before a high intensity interval training (HIIT) exercise, immediately after exercise, and 1 hour after exercise. We additionally tested subjects’ cognitive performance at these time points through a memory task and two executive function tasks. We found that whole brain stiffness decreased in nearly all subjects immediately after exercise by an average of 4.2% (p<0.0001) and that whole brain damping ratio increased by an average of 3.1% (p=0.001). Performance on all three cognitive tasks improved immediately after exercise (p<0.05).

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