A method to increase the resolution of sodium images from simultaneous 1H MRF/23Na MRI
Gonzalo G Rodriguez1, Zidan Yu1,2, Lauren O'Donnell1, Liz Calderon1, Sarah Shaykevich2, Martijn A Cloos3,4, and Guillaume Madelin1,2
1Center for Biomedical Imaging, Department of Radiology, New York University School of Medicine, New York, NY, United States, 2Vilcek Institute of Graduate Biomedical Sciences, NYU Langone Health, New York, NY, United States, 3Centre for Advanced Imaging, The University of Queensland, Brisbane, Australia, 4ARC Training Centre for Innovation in Biomedical Imaging Technology, The University of Queensland, Brisbane, Australia
In this work, we present an algorithm to generate a high-resolution 23Na image from simultaneously-acquired low-resolution 23Na density-weighted MRI (2.85×2.85×5 mm3) and high-resolution 1H density, T1, and T2 maps from MRF (1.5×1.5×5 mm3) in brain at 7 T. As a result, the mean value of the difference between the generated and ground truth high-resolution 23Na images is 0.5% with a standard deviation of 6.2% and multi-scale structural similarity index of 0.97.
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