Longitudinal Changes of White Matter Hyperintensities Following Hemodialysis Initiation in Old Adults: A Prospective Pilot Study
Xiufeng Li1, Gregory J. Metzger1, and Anne M. Murray2,3,4
1Center for Magnetic Resonance Research, University of Minnesota, Minneapolis, MN, United States, 2Hennepin HealthCare Research Institute, Hennepin Healthcare, Minneapolis, MN, United States, 3Department of Medicine, University of Minnesota, Minneapolis, MN, United States, 4Geriatrics Division, Department of Medicine, Hennepin Healthcare, Minneapolis, MN, United States
Repeated conventional hemodialysis may result in permanent cerebrovascular dysfunction that can initiate and exacerbate other cerebral structural abnormalities. Until today, the longitudinal WMH burden changes in old end-stage renal disease (ESRD) patients following the initiation of hemodialysis treatment have not been specifically studied. We performed a prospective pilot study with a hypothesis that WMH burden increases following the initiation of hemodialysis in old ESRD patient. Our study results suggested that WMH burdens increased significantly after the initiation of hemodialysis treatment.
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