We assessed blood-flow velocity measurements on 7T MRI as a potential disease marker for cerebral small vessel disease (SVD). Two-dimensional phase-contrast velocity measurements were performed in perforating arteries of the basal ganglia (BG) and white matter of the centrum semiovale (CSO) in patients with sporadic SVD and age- and sex-matched controls. Pulsatility index (PI) was significantly higher in the BG, in patients (0.45 [0.41–0.49] vs. 0.36 [0.30–0.41] in controls) (p=0.02). In the CSO, similar number of vessels, mean velocity, and PI were observed between patients and controls. BG pulsatility could be a potential marker for SVD.
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