In-vivo Absolute Multinuclear Thermometry (AMT) in a Rat Model
Omid Yaghmazadeh1, Mihaly Voroslakos1, Mark Mattingly2, Zakia Ben Youss Gironda3, Youssef Zaim Wadghiri3, Seena Dehkharghani3,4, and Leeor Alon3,4
1Neuroscience, New York University School of Medicine, New York, NY, United States, 2Bruker cooperation, Billerica, MA, United States, 3Department of Radiology, New York University School of Medicine, New York, NY, United States, 4Center for Advanced Imaging Innovation and Research (CAI2R), New York University School of Medicine, New York, NY, United States
We introduce an in-vivo multinuclear MR thermometry technique which utilizes the unique frequency shift between water and sodium resonant frequencies. Reconstruction of the absolute temperature is validated using chemical shift imaging conducted on a rodent model implanted with a thin fiber optic probe for monitoring.
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