Abstract #0445

In-vivo Absolute Multinuclear Thermometry (AMT) in a Rat Model

Omid Yaghmazadeh¹, Mihaly Voroslakos¹, Mark Mattingly², Zakia Ben Youss Gironda³, Youssef Zaim Wadghiri³, Seena Dehkharghani^3,4, and Leeor Alon^3,4

¹Neuroscience, New York University School of Medicine, New York, NY, United States, ²Bruker cooperation, Billerica, MA, United States, ³Department of Radiology, New York University School of Medicine, New York, NY, United States, ⁴Center for Advanced Imaging Innovation and Research (CAI2R), New York University School of Medicine, New York, NY, United States

Synopsis

We introduce an in-vivo multinuclear MR thermometry technique which utilizes the unique frequency shift between water and sodium resonant frequencies. Reconstruction of the absolute temperature is validated using chemical shift imaging conducted on a rodent model implanted with a thin fiber optic probe for monitoring.

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