Repetitive head impact (RHI) increases the risk of concussion, probably due to alterations of the brain-skull mechanical coupling. It would be of clinical value to have a reliable biomarker capable of assessing the status of the brain-skull coupling condition. MRE-based normalized octahedral shear strain (NOSS) has been proposed as a method for such brain membrane system evaluation. To verify the test-retest reliability of NOSS, datasets from 14 healthy volunteers were acquired with different vibration directions and within- and between-day scanning. This study demonstrated the excellent repeatability of the proposed method, showing the NOSS distributions were robust to loading variations.
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