Meeting Banner
Abstract #0519

Tractography protocols for the neonatal brain, standardised against the adult human and macaque

Shaun of Warrington1, Elinor Thompson1, Jessica Dubois2, Luke Baxter3, Rebeccah Slater3, Rogier B Mars4,5, Saad Jbabdi4, Matteo Bastiani1, and Stamatios N Sotiropoulos1,4,6
1Sir Peter Mansfield Imaging Centre, School of Medicine, University of Nottingham, Nottingham, United Kingdom, 2University of Paris, Inserm, NeuroDiderot Unit; University Paris-Saclay, CEA, NeuroSpin center, Paris, France, 3Department of Paediatrics, University of Oxford, Oxford, United Kingdom, 4Wellcome Centre for Integrative Neuroimaging, FMRIB Centre, Nuffield Department of Clinical Neurosciences, University of Oxford, Oxford, United Kingdom, 5Donders Institute for Brain, Cognition and Behaviour, Radboud University, Nijmegen, Nijmegen, Netherlands, 6National Institute for Health Research (NIHR) Nottingham Biomedical Research Centre, Nottingham, United Kingdom

Synopsis

The neonatal brain undergoes rapid development in the months after birth. Diffusion tractography is a unique method for probing developing white matter connections. We present a novel and comprehensive library of tractography protocols for the neonatal brain, whilst ensuring correspondence with previously developed protocols for the adult and macaque brain. We demonstrate protocol robustness across data quality and show that the resultant tracts capture a-priori known trends in white matter microstructure. We show that these protocols open avenues for quantitative comparisons across the lifespan, but also species, which we exemplify by revealing developmental trends in connectivity patterns.

How to access this content:

For one year after publication, abstracts and videos are only open to registrants of this annual meeting. Registrants should use their existing login information. Non-registrant access can be purchased via the ISMRM E-Library.

After one year, current ISMRM & ISMRT members get free access to both the abstracts and videos. Non-members and non-registrants must purchase access via the ISMRM E-Library.

After two years, the meeting proceedings (abstracts) are opened to the public and require no login information. Videos remain behind password for access by members, registrants and E-Library customers.

Click here for more information on becoming a member.

Keywords