Meeting Banner
Abstract #0525

Along-tract quantification of the BOLD hemodynamic response function in white matter

Kurt G Schilling1, Muwei Li1, Francois Rheault2, Yurui Gao2, Zhaohua Ding2, Adam W Anderson2, Hakmook Kang2, Bennett A Landman2, and John C Gore1
1Vanderbilt University Medical Center, Nashville, TN, United States, 2Vanderbilt University, Nashville, TN, United States


We measured the variations of the BOLD hemodynamic response function (HRF) along white matter (WM) pathways. We find that the WM HRF is different to that of the gray matter (GM), and has a prominent negative dip and smaller peak signal. Further, we find that the HRF changes along WM pathways, and is different between pathways. Characterizing the variations of the WM HRF along and across pathways may provide insight into the biophysical basis of BOLD effects in WM and the relationships between WM structure and neurovascular coupling.

This abstract and the presentation materials are available to members only; a login is required.

Join Here