Abstract #0526

Tracking rapid stimulus-driven BOLD oscillations in the human primary motor cortex and somatosensory cortex

Shota Hodono^1,2, Jonathan R Polimeni^3,4, David Reutens^1,2, and Martijn A Cloos^1,2

¹Centre for Advanced Imaging,The University of Queensland, Brisbane, Australia, ²ARC Training Centre for Innovation in Biomedical Imaging Technology, The University of Queensland, Brisbane, Australia, ³Athinoula A. Martinos Center for Biomedical Imaging, Department of Radiology, Harvard Medical School, Massachusetts General Hospital, Charlestown, MA, United States, ⁴Division of Health Sciences and Technology, Massachusetts Institute of Technology, Cambridge, MA, United States

Synopsis

We investigated the observable frequency range of stimulus-driven BOLD oscillations in human M1 and S1. Experimental results showed that BOLD response oscillations up to 0.50 Hz can be measured in individual subjects. The responses were substantially higher than predicted using the canonical HRF model. Despite their angio-architectural differences, M1 and S1 showed similar nonlinearities in their response. Viewed across cortical depths, M1 and S1 showed different behaviors in terms of response amplitude and especially phase as a function of stimulus frequency.

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