4D-dynamic MRI were collected and utilized to track unconstrained movement of individual wrist carpal bones in 31 asymptomatic volunteer subjects. Rotational and translational trajectories of the scaphoid, lunate, and capitate bones were collected and processed using a novel multi-subject profile registration and analysis engine. Morphological images were analyzed by an expert radiologist to identify asymptomatic abnormalities within the cohort. Statistical parametric mapping of each profile was performed to identify normative variances of each profile metric and correlation with identified abnormalities. The study presents methodological approaches and normative baseline profile metrics of value to future studies of symptomatic wrists.
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