The in-vivo imaging of iron and myelin concentrations along cortical laminae in the brain has significance in advancing knowledge about the roles of iron and myelin in brain function and in disease. In this study, we apply χ-separation, a recently developed advanced susceptibility imaging method, to explore changes in iron and myelin content throughout the cortex and into the white matter. Our findings show that iron and myelin peak at different laminar surfaces and that there is regional differences in the intensity profiles. The results suggest regional and laminar variation of iron and myelin throughout the brain.
How to access this content:
For one year after publication, abstracts and videos are only open to registrants of this annual meeting. Registrants should use their existing login information. Non-registrant access can be purchased via the ISMRM E-Library.
After one year, current ISMRM & ISMRT members get free access to both the abstracts and videos. Non-members and non-registrants must purchase access via the ISMRM E-Library.
After two years, the meeting proceedings (abstracts) are opened to the public and require no login information. Videos remain behind password for access by members, registrants and E-Library customers.
Keywords