Abstract #0605

Free Breathing Abdominal Tissue Quantification using 2D MR Fingerprinting with quadratic RF phase (qRF-MRF)

Sherry Huang¹, Yong Chen², Reid Bolding³, Leonardo Kayat Bittencourt^2,4, Mark A Griswold², and Rasim Boyacioglu²

¹Biomedical Engineering, Case Western Reserve University, Cleveland, OH, United States, ²Radiology, Case Western Reserve University, Cleveland, OH, United States, ³Physics, Case Western Reserve University, Cleveland, OH, United States, ⁴Radiology, University Hospitals Cleveland Medical Center, Cleveland, OH, United States

Synopsis

This study presents a Pilot Tone (PT) based free-breathing technique for two-dimensional simultaneous quantification of T1, T2, T2*, fat fraction (FF), and water fraction (WF) using quadratic RF phase Magnetic Resonance Fingerprinting (qRF-MRF). We report the quantitative comparison of a cohort of 10 healthy subjects between free-breathing and breath-hold qRF-MRF as well as the comparison to standard clinical protocols. Free-breathing results are comparable to both breath-hold and standard clinical protocols (p > 0.05), indicating the stability and reproducibility of the method.

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