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Abstract #0626

Parallel Transmit T2 Preparation for 3D T2 Mapping at Ultra-High Field

Gabriele Bonanno1,2,3, Patrick Liebig4, Kurt Majewsky5, Tobias Kober6,7,8, and Tom Hilbert6,7,8
1Advanced Clinical Imaging Technology, Siemens Healthcare AG, Bern, Switzerland, 2Magnetic Resonance Methodology, Institute of Diagnostic and Interventional Neuroradiology, University of Bern, Bern, Switzerland, 3Translational Imaging Center, sitem-insel, Bern, Switzerland, 4Siemens Healthcare GmbH, Erlangen, Germany, 5Siemens AG, Munich, Germany, 6Advanced Clinical Imaging Technology, Siemens Healthcare AG, Lausanne, Switzerland, 7Department of Radiology, University Hospital (CHUV) and University of Lausanne (UNIL), Lausanne, Switzerland, 8LTS5, École Polytechnique Fédérale de Lausanne, Lausanne, Switzerland

Synopsis

T2 relaxometry at ultra-high field has the potential to become an important quantitative MRI biomarker thanks to its sensitivity to pathology. However, acquiring high-resolution isotropic T2 maps is challenging due to signal-to-noise and specific absorption rate constraints. We present a T2-mapping method for ultra-high-field MRI based on a parallel transmit T2-preparation (T2p) module integrated in a compressed sensing accelerated segmented 3D FLASH sequence. The proposed parallel transmit T2p module is investigated in phantom and in vivo experiments and compared to an adiabatic T2p module. Preliminary tests show feasibility for sub-millimeter T2 relaxometry at 7 T.

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Abstract

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