This work presents a complex-based fitting method to address concomitant gradient (CG) phase errors for time-interleaved (i.e., multi-pass) chemical shift-encoded (CSE) MRI estimation of proton density fat fraction (PDFF) and R2* through a joint estimation of pass-specific phase terms. The proposed method does not require prior knowledge of gradient waveforms. The proposed fitting method removed significant PDFF and R2* estimation errors in both phantom and in vivo evaluations away from isocenter. An evaluation in 29 clinical liver datasets demonstrated reduced PDFF bias and variability (8.4% improvement in the coefficient of variation), even when the imaging volume was centered at isocenter.
This abstract and the presentation materials are available to members only; a login is required.