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Abstract #0773

Diffusion-filtered imaging: Towards tissue-specific diffusion-MRI contrasts by combinations of tensor-valued diffusion encoding

Filip Szczepankiewicz1, Geraline Vis1, Danielle van Westen1, Carl-Fredrik Westin2, Pia M Sundgren1, and Markus Nilsson1
1Clinical Sciences Lund, Lund University, Lund, Sweden, 2Radiology, Brigham and Women's Hospital, Boston, MA, United States


Diffusion weighted imaging has been used both as a radiological tool that provides a simple biomarker without quantitative qualities, and more recent efforts have endeavored to make it quantitative by fitting of biophysical models or representations. In this work, we explore the novel radiological contrasts that can be generated by introducing tensor-valued diffusion encoding. Unlike most model-based approaches, these contrasts can be produced by rapid acquisition schemes and they produce novel contrasts that may contribute new diagnostic and radiological biomarkers.

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