Abstract #0774

Resolve fiber crossings using orientation distribution function (ODF) of decomposed sub-voxel paramagnetic and diamagnetic susceptibility

Jingjia Chen¹, Dimitrios Gkotsoulias², Jennifer Jaffe^3,4, Catherine Crockford^3,4, Roman Wittig^3,4, Harald E. Möller², and Chunlei Liu^1,5

¹Electrical Engineering and Computer Sciences, University of California, Berkeley, Berkeley, CA, United States, ²Max Planck Institute for Human Cognitive and Brain Sciences, Leipzig, Germany, ³Max Planck Institute for Evolutionary Anthropology, Leipzig, Germany, ⁴Taï Chimpanzee Project, Centre Suisse de Recherches Scientifiques en Côte d’Ivoire, Abidjan, Cote D'ivoire, ⁵Helen Wills Neuroscience Institute, University of California, Berkeley, Berkeley, CA, United States

Synopsis

DECOMPOSE-QSM was applied on high angular-resolution multi-echo gradient-echo data of a chimpanzee brain to evaluate its ability in resolving orientation mixture of substructure fiber bundles. The orientation distribution function (ODF) of the separated paramagnetic and diamagnetic susceptibility provides smooth transitions of multiple fiber orientations. Additionally, the paramagnetic maps from DECOMPOSE show a potential to resolve fiber crossings in deep gray matter regions.

How to access this content:

For one year after publication, abstracts and videos are only open to registrants of this annual meeting. Registrants should use their existing login information. Non-registrant access can be purchased via the ISMRM E-Library.

After one year, current ISMRM & ISMRT members get free access to both the abstracts and videos. Non-members and non-registrants must purchase access via the ISMRM E-Library.

After two years, the meeting proceedings (abstracts) are opened to the public and require no login information. Videos remain behind password for access by members, registrants and E-Library customers.

Click here for more information on becoming a member.