To test the feasibility of brain perfusion imaging exploiting flow-related enhancement during fast gradient echo sequences. Imaging was performed using Fast Low-Angle Shot (FLASH) and balanced steady-state free precession (bSSFP) sequences of a single axial slice with various imaging parameters at 1.5T and 3T. Perfusion-weighted maps were generated based on the Fourier decomposition method “Phase-REsolved FUnctional Lung” (PREFUL) MRI. The derived imaging protocol was evaluated in patients with metastases and a stroke showing high spatial overlap to post-contrast MRI and CT-perfusion. A cohort of 19 healthy individuals presented moderate, but significant regional correlation and high spatial Dice overlap to pCASL-MRI.
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