The recently introduced axial-symmetric DKI framework is less noise sensitive but unable to capture more complex fiber configurations causing an AxDKI inherent bias in those voxels. We found that the parallel and perpendicular kurtosis are most often affected by this inherent bias and that it translates to the AxDKI based biophysical parameters. Bias-free estimation of the biophysical parameters with the AxDKI framework, therefore, is difficult if not impossible at this point. However, the parallel and perpendicular diffusivity and the mean kurtosis were largely bias-free, encouraging use of the AxDKI framework in studies where these parameters are focused on.
How to access this content:
For one year after publication, abstracts and videos are only open to registrants of this annual meeting. Registrants should use their existing login information. Non-registrant access can be purchased via the ISMRM E-Library.
After one year, current ISMRM & ISMRT members get free access to both the abstracts and videos. Non-members and non-registrants must purchase access via the ISMRM E-Library.
After two years, the meeting proceedings (abstracts) are opened to the public and require no login information. Videos remain behind password for access by members, registrants and E-Library customers.
Keywords