Mapping of apparent Intra- and extra-myocellular lipid content using spiral spectroscopic imaging and diffusion imaging at 3T
Antoine Naëgel1,2, Magalie Viallon1, Jabrane Karkouri1,2,3, Thomas Troalen2, Kevin Moulin1,2, Pierre Croisille1, and Hélène Ratiney1
1Université de Lyon, INSA-Lyon, Université Claude Bernard Lyon 1, UJM-Saint Etienne, CNRS, Inserm, CREATIS UMR 5220, U1206, Lyon, France, 2Siemens Healthineers, Saint-Denis, France, 3Wolfson Brain Imaging Center, University of Cambridge, Cambridge, United Kingdom
Exploring spatial distribution of intra- and extramyocellular lipids linked to the orientation of muscle fibers is complex. We used a magnetic resonance spectroscopic imaging (MRSI) technique with a spiral encoding of k-t space and diffusion imaging tractography at 3T to reveal possible concomitant factors. The IMCL preponderance index, exploiting the spectroscopic dimension and proposed in this study, highlights interesting and relevant patterns in some calf muscle heads.
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