Surgical palliation of single ventricular heart disease (Fontan procedure) leads to poor cardiac output, high central venous pressures, and long-term multiorgan morbidity. We report cerebral blood flow, brain oxygen delivery, and cerebral metabolic rate in 20 Fontan survivors and 9 control subjects. Fontan patients had lower cerebral blood flow and oxygen saturation but maintained cerebral oxygen delivery and cerebral metabolic rate of oxygen (CMRO2) because of polycythemia. Scattergram between CMRO2 and O2 delivery suggests similar oxygen extraction at the microvascular level in both groups. Taken together, these data suggest adequate cerebrovascular compensation to low cardiac output in Fontan patients.
How to access this content:
For one year after publication, abstracts and videos are only open to registrants of this annual meeting. Registrants should use their existing login information. Non-registrant access can be purchased via the ISMRM E-Library.
After one year, current ISMRM & ISMRT members get free access to both the abstracts and videos. Non-members and non-registrants must purchase access via the ISMRM E-Library.
After two years, the meeting proceedings (abstracts) are opened to the public and require no login information. Videos remain behind password for access by members, registrants and E-Library customers.
Keywords