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Abstract #1129

Evaluating of Deep Brain Nuclei Iron Deposition in Primary Grade 1 Hypertension Patients by QSM: A Preliminary Study

Shiyun Zhang1, Kunhua Wu2, Guoli Bi2, Shaoyu Wang3, Yunzhu Wu3, Guoqing Xie4, and Qian Wang4
1Dali university, Dali, China, 2The First People's Hospital of Yunnan Province, Kunming, China, 3MR Scientific Marketing, Siemens Healthineers, Shanghai, China, 4Kunming University of Science and Technology, Kunming, China


Hypertension is becoming a common health problem all over the world. In this study, Quantitative Susceptibility Mapping (QSM) was used to compare the differences of iron deposition in deep brain nuclei between 28 primary grade 1 hypertension (PG1H) patients and 28 age-sex-matched healthy controls (HC). The results showed that the iron deposition in six deep brain nuclei ROIs were higher in PG1H than in HC. This study laid a foundation for exploring the relationship between the hypertension severity and iron deposition in deep brain nuclei. It was also of great significance for clinical exploration of the physiological and pathological mechanism of hypertension and the correct selection of the treatment scheme of hypertension.

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