Abstract #1129

Evaluating of Deep Brain Nuclei Iron Deposition in Primary Grade 1 Hypertension Patients by QSM: A Preliminary Study

Shiyun Zhang¹, Kunhua Wu², Guoli Bi², Shaoyu Wang³, Yunzhu Wu³, Guoqing Xie⁴, and Qian Wang⁴

¹Dali university, Dali, China, ²The First People's Hospital of Yunnan Province, Kunming, China, ³MR Scientific Marketing, Siemens Healthineers, Shanghai, China, ⁴Kunming University of Science and Technology, Kunming, China

Synopsis

Hypertension is becoming a common health problem all over the world. In this study, Quantitative Susceptibility Mapping (QSM) was used to compare the differences of iron deposition in deep brain nuclei between 28 primary grade 1 hypertension (PG1H) patients and 28 age-sex-matched healthy controls (HC). The results showed that the iron deposition in six deep brain nuclei ROIs were higher in PG1H than in HC. This study laid a foundation for exploring the relationship between the hypertension severity and iron deposition in deep brain nuclei. It was also of great significance for clinical exploration of the physiological and pathological mechanism of hypertension and the correct selection of the treatment scheme of hypertension.

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