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Abstract #1130

Relationships Between Muscle Function, Muscle Fat, and Architecture Measured by MRI in Vivo

Joseph A. Gordon III1, Nicholas M. Remillard1, Luke R. Arieta1, Rajakumar M. Nagarajan1,2, Bruce M. Damon3,4, and Jane A. Kent1,2
1Kinesiology, University of Massachusetts Amherst, Amherst, MA, United States, 2Institute for Applied Life Sciences, University of Massachusetts Amherst, Amherst, MA, United States, 3Carle Clinical Imaging Research Program, Carle Health, Urbana, IL, United States, 4Stephens Family Clinical Research Institute, Carle Health, Urbana, IL, United States


The purpose of this work was to investigate the associations between skeletal muscle function and markers of fat content, diffusivity, and architecture. Combining MR techniques that measure muscle structure in vivo with muscle strength measures can elucidate mechanisms other than muscle size that may contribute to functional impairments. This study identified variables (e.g., fascicle length, muscle curvature, pennation angle, fat fraction) that are worthy of investigation in conjunction with functional parameters in future research, and highlighted assessment of muscle function across various contraction types and velocities.

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