Current evaluation methods of rehabilitation following acute musculoskeletal injuries are largely qualitative. MRI and biomechanics tools can provide sensitive, quantitative measures of knee joint and lower extremity muscle changes, but the relationship between MRI and gait markers is not well characterized. We combined an MRI protocol with wearable sensors in healthy participants to characterize the relationship between gait kinematic asymmetries and thigh muscle and cartilage morphology and composition. We show that vastus lateralis (VL) muscle microstructure assessed via Diffusion Tensor Imaging (DTI) may be sensitive to gait variations. Future work may further explore these correlations in patients with musculoskeletal injuries.
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