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Abstract #1143

Quantitative measurements of GABA in mouse brain using MR Spectroscopy at 7T

Mohamed Tachrount1, Jason Lerch1,2, and Stuart Clare1
1Wellcome Centre for Integrative Neuroimaging (FMRIB), Nuffield Department of Clinical Neurosciences, University of Oxford, Oxford, United Kingdom, 2Mouse Imaging Centre (MICe), University of Toronto, Toronto, ON, Canada

Synopsis

The goals of this study were to implement a MEGA-sLASER sequence with prospective field drift correction on a preclinical scanner, develop the processing tools and validate them on a group of wild type mice.

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