Abstract #1143

Quantitative measurements of GABA in mouse brain using MR Spectroscopy at 7T

Mohamed Tachrount¹, Jason Lerch^1,2, and Stuart Clare¹

¹Wellcome Centre for Integrative Neuroimaging (FMRIB), Nuffield Department of Clinical Neurosciences, University of Oxford, Oxford, United Kingdom, ²Mouse Imaging Centre (MICe), University of Toronto, Toronto, ON, Canada

Synopsis

The goals of this study were to implement a MEGA-sLASER sequence with prospective field drift correction on a preclinical scanner, develop the processing tools and validate them on a group of wild type mice.

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