Hyperpolarized xenon-129 (HXe) imaging is capable of quantifying lung function through measurements of ventilation and gas exchange. However, traditional HXe approaches rely on long breath-holds for imaging, which may not be representative of steady-state behavior and are limited by the volume of gas that can be delivered. In this work, we imaged gas- and dissolved-phase xenon continuously over approximately 50 breaths and retrospectively binned the images, generating dynamic maps encompassing the entire respiratory cycle.
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