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Abstract #1280

Assessing the repeatability of tissue sodium concentration and characterizing the bi-exponential T2* decay signal in the calf

Ben Prestwich1 and Susan Francis1
1Sir Peter Mansfield Imaging Centre, University of Nottingham, Nottingham, United Kingdom


The repeatability of sodium (23Na) MRI measures must be understood to allow for its application in clinical studies of patient groups or response to therapy. A series of 23Na scans were performed on the calf of healthy subjects, this included a 3D GRE 23Na scan and phase sensitive B1 mapping to measure tissue sodium concentration (TSC). Subjects were scanned twice for assessment of repeatability of measures. A multi echo UTE scan was used to measure the T2* decay. TSC was shown to have a coefficient of variation of 16±4 % between visits and the bi-exponential decay curve was characterized.

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