The repeatability of sodium (23Na) MRI measures must be understood to allow for its application in clinical studies of patient groups or response to therapy. A series of 23Na scans were performed on the calf of healthy subjects, this included a 3D GRE 23Na scan and phase sensitive B1 mapping to measure tissue sodium concentration (TSC). Subjects were scanned twice for assessment of repeatability of measures. A multi echo UTE scan was used to measure the T2* decay. TSC was shown to have a coefficient of variation of 16±4 % between visits and the bi-exponential decay curve was characterized.
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