Evaluation of 23Na relaxation times and concentrations in the patellar knee cartilage at 3T
Benedikt Kamp1, Miriam Frenken1, Jan M. Henke1,2, Daniel B. Abrar1, Armin M. Nagel3,4, Lena V. Gast3, Georg Oeltzschner5,6, Lena M. Wilms1, Sven Nebelung1, Gerald Antoch1, Hans-Jörg Wittsack1, and Anja Müller-Lutz1
1University Dusseldorf, Medical Faculty, Department of Diagnostic and Interventional Radiology, Dusseldorf, Germany, 2University Dusseldorf, Medical Faculty, Clinic of Nuclear Medicine, Dusseldorf, Germany, 3Institute of Radiology, University Hospital Erlangen, Friedrich-Alexander-Universität Erlangen-Nürnberg 14 (FAU), Erlangen, Germany, 4Division of Medical Physics in Radiology, German Cancer Research Center (DKFZ), Heidelberg, Germany, 5Russell H. Morgan Department for Radiology and Radiological Science, The Johns Hopkins University 18 School of Medicine, Baltimore, MD, United States, 6F. M. Kirby Research Center for Functional Brain Imaging, Kennedy Krieger Institute, Baltimore, MD, United States
23Na relaxation times and concentrations were measured in patellar cartilage with a clinical 3T MRI scanner. Because of the low resolution in 23Na imaging, a focus was set on reducing the influence of synovial fluid. To estimate T1 a biexponential two-compartment fitting model was applied. In T2* measurements, an inversion pulse was used to suppress the signal from synovial fluid. 23Na parameters were successfully determined and are in good accordance to literature results measured at higher field strengths.
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