Biomechanical models coupled with cardiovascular MRI (CMR) have the potential to provide non-invasively physiological parameters of clinical interest. The approach is presented and validated on a group of 10 patients who underwent CMR and invasive catheterization. Patient-specific models are built based on CMR data and maximum/minimum arterial pressure. The stroke work, derived from ventricular pressure-volume (P-V) loops, was comparable between the measured and simulated P-V loops, suggesting the high quality of the in silico loops. An excellent correlation of the model-derived myocardial contractility with maximum time-derivative of ventricular pressure gives an opportunity for the non-invasive characterization of patients’ inotropic state.
How to access this content:
For one year after publication, abstracts and videos are only open to registrants of this annual meeting. Registrants should use their existing login information. Non-registrant access can be purchased via the ISMRM E-Library.
After one year, current ISMRM & ISMRT members get free access to both the abstracts and videos. Non-members and non-registrants must purchase access via the ISMRM E-Library.
After two years, the meeting proceedings (abstracts) are opened to the public and require no login information. Videos remain behind password for access by members, registrants and E-Library customers.
Keywords