Pancreatic ductal adenocarcinoma (PDAC) is among the deadliest of cancers. We recently showed that deuterium metabolic imaging (DMI) can serve as a potential method for PDAC’s detection; we also demonstrated that multi-echo balanced steady-state free precession (ME-bSSFP) can greatly increase DMI’s SNR per unit time compared to CSI acquisitions. This study synergizes these aspects, to provide high resolution maps on the metabolic kinetic of PDAC and pancreatitis mouse models. ME-bSSFP at 15.2T showed that lactate accumulated in different kinds of tumors. In general, glucose was also uptaken by the tumors, and HDO concentrated in them.
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