Abstract #1423

Susceptibility corrected Proton Resonance Frequency Shift based MR Thermometry of hepatic Microwave Ablation in an in-vivo swine model

Marcel Gutberlet^1,2, Enrico Pannicke^2,3, Inga Bruesch⁴, Regina Rumpel⁴, Eva-Maria Wittauer⁴, Florian W. R. Vondran⁵, Frank Wacker^1,2, and Bennet Hensen^1,2

¹Institute of Diagnostic and Interventional Radiology, Medical School Hannover, Hannover, Germany, ²STIMULATE-Solution Centre for Image Guided Local Therapies, Magdeburg, Germany, ³Department Biomedical Magnetic Resonance, Otto-von-Guericke University, Magdeburg, Germany, ⁴Institute for Laboratory Animal Science and Central Animal Facility, Medical School Hannover, Hannover, Germany, ⁵Clinic for General, Abdominal and Transplant Surgery, Medical School Hannover, Hannover, Germany

Synopsis

In microwave ablation (MWA), heat induced susceptibility changes impair the assessment of the ablation zones using proton resonance frequency shift based magnetic resonance (MR) thermometry. In this work, these heat related field changes were modelled to improve the accuracy of MR thermometry to monitor microwave ablation. In a study of hepatic MWA in an in-vivo swine model, the proposed method provided increased accuracy to assess the ablation zone compared to uncorrected MR thermometry.

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