Meeting Banner
Abstract #1424

Voxelwise estimation of multiple response functions and fiber orientation distribution functions in diffusion MRI

Samuel St-Jean1,2, Alexander Leemans3, Filip Szczepankiewicz1, Christian Beaulieu2, and Markus Nilsson1
1Clinical Sciences Lund, Lund University, Lund, Sweden, 2University of Alberta, Edmonton, AB, Canada, 3Image Sciences Institute, UMC Utrecht, Utrecht, Netherlands


We present a framework to compute a response function for each voxel using a fingerprinting approach and a per voxel, per compartment estimation of the fiber orientation distribution (FOD) function for diffusion MRI. The method first matches the powder-averaged signal to a database of candidate signals and estimates a unique FOD from this matched signal for each compartment. This is done by turning the candidate signals into continuous Legendre polynomials, leading to a set of linear equations to estimate coefficients of the FODs, without requiring a prior segmentation or averaging multiple response functions.

This abstract and the presentation materials are available to members only; a login is required.

Join Here