Gadolinium-enhanced imaging provides valuable information in clinical practice. Concerns raised by gadolinium depositions favors strategies reducing injected doses in patients requiring repeated scans. We designed four phantoms containing serial dilutions of four gadolinium-based contrast agents to compare their efficacy for low-Gd concentration detection in clinically used MR sequences, based on signal intensity and contrast-to-noise ratio. We performed a preliminary study comparing T1-TSE, FLAIR and FLAIR with optimized parameters on these phantoms. The optimized FLAIR sequence shows an efficient detection of low concentrations, in particular using gadobutrol or gadoteridol.
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